Mediation of Drosophila autosomal dosage effects and compensation by network interactions

BACKGROUND: Gene dosage change is a mild perturbation that is a valuable tool for pathway reconstruction in Drosophila. While it is often assumed that reducing gene dose by half leads to two-fold less expression, there is partial autosomal dosage compensation in Drosophila, which may be mediated by...

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Detalles Bibliográficos
Autores principales: Malone, John H, Cho, Dong-Yeon, Mattiuzzo, Nicolas R, Artieri, Carlo G, Jiang, Lichun, Dale, Ryan K, Smith, Harold E, McDaniel, Jennifer, Munro, Sarah, Salit, Marc, Andrews, Justen, Przytycka, Teresa M, Oliver, Brian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2012
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3446302/
https://www.ncbi.nlm.nih.gov/pubmed/22531030
http://dx.doi.org/10.1186/gb-2012-13-4-r28

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3446302/
https://www.ncbi.nlm.nih.gov/pubmed/22531030
http://dx.doi.org/10.1186/gb-2012-13-4-r28

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