Genetic basis of transcriptome differences between the founder strains of the rat HXB/BXH recombinant inbred panel

BACKGROUND: With the advent of next generation sequencing it has become possible to detect genomic variation on a large scale. However, predicting which genomic variants are damaging to gene function remains a challenge, as knowledge of the effects of genomic variation on gene expression is still li...

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Detalles Bibliográficos
Autores principales: Simonis, Marieke, Atanur, Santosh S, Linsen, Sam, Guryev, Victor, Ruzius, Frans-Paul, Game, Laurence, Lansu, Nico, de Bruijn, Ewart, van Heesch, Sebastiaan, Jones, Steven JM, Pravenec, Michal, Aitman, Tim J, Cuppen, Edwin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3446305/
https://www.ncbi.nlm.nih.gov/pubmed/22541052
http://dx.doi.org/10.1186/gb-2012-13-4-r31