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Functional annotation of the human brain methylome identifies tissue-specific epigenetic variation across brain and blood
BACKGROUND: Dynamic changes to the epigenome play a critical role in establishing and maintaining cellular phenotype during differentiation, but little is known about the normal methylomic differences that occur between functionally distinct areas of the brain. We characterized intra- and inter-indi...
Autores principales: | , , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3446315/ https://www.ncbi.nlm.nih.gov/pubmed/22703893 http://dx.doi.org/10.1186/gb-2012-13-6-r43 |