Phosphorylated and sumoylation-deficient progesterone receptors drive proliferative gene signatures during breast cancer progression

INTRODUCTION: Progesterone receptors (PR) are emerging as important breast cancer drivers. Phosphorylation events common to breast cancer cells impact PR transcriptional activity, in part by direct phosphorylation. PR-B but not PR-A isoforms are phosphorylated on Ser294 by mitogen activated protein...

Descripción completa

Detalles Bibliográficos
Autores principales: Knutson, Todd P, Daniel, Andrea R, Fan, Danhua, Silverstein, Kevin AT, Covington, Kyle R, Fuqua, Suzanne AW, Lange, Carol A
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3446358/
https://www.ncbi.nlm.nih.gov/pubmed/22697792
http://dx.doi.org/10.1186/bcr3211

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3446358/
https://www.ncbi.nlm.nih.gov/pubmed/22697792
http://dx.doi.org/10.1186/bcr3211

Ejemplares similares