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Phosphorylated and sumoylation-deficient progesterone receptors drive proliferative gene signatures during breast cancer progression

INTRODUCTION: Progesterone receptors (PR) are emerging as important breast cancer drivers. Phosphorylation events common to breast cancer cells impact PR transcriptional activity, in part by direct phosphorylation. PR-B but not PR-A isoforms are phosphorylated on Ser294 by mitogen activated protein...

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Detalles Bibliográficos
Autores principales:	Knutson, Todd P, Daniel, Andrea R, Fan, Danhua, Silverstein, Kevin AT, Covington, Kyle R, Fuqua, Suzanne AW, Lange, Carol A
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2012
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3446358/ https://www.ncbi.nlm.nih.gov/pubmed/22697792 http://dx.doi.org/10.1186/bcr3211

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