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BRCA1 as a tumor suppressor linked to the regulation of epigenetic states: keeping oncomiRs under control

BRCA1 is a tumor suppressor gene known to be implicated in the development of a subset of breast and ovarian cancers. The tumor suppressor properties of BRCA1 are generally thought to be linked to the gene's critical roles in the network of DNA damage response. In a recent report, BRCA1-mediate...

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Detalles Bibliográficos
Autores principales: Stefansson, Olafur Andri, Esteller, Manel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3446364/
https://www.ncbi.nlm.nih.gov/pubmed/22423979
http://dx.doi.org/10.1186/bcr3119