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Aromatase inhibitors, estrogens and musculoskeletal pain: estrogen-dependent T-cell leukemia 1A (TCL1A) gene-mediated regulation of cytokine expression

INTRODUCTION: Arthralgias and myalgias are major side effects associated with aromatase inhibitor (AI) therapy of breast cancer. In a recent genome-wide association study, we identified SNPs - including one that created an estrogen response element near the 3' end of the T-cell leukemia 1A (TCL...

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Detalles Bibliográficos
Autores principales: Liu, Mohan, Wang, Liewei, Bongartz, Tim, Hawse, John R, Markovic, Svetomir N, Schaid, Daniel J, Mushiroda, Taisei, Kubo, Michiaki, Nakamura, Yusuke, Kamatani, Naoyuki, Goss, Paul E, Ingle, James N, Weinshilboum, Richard M
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3446375/
https://www.ncbi.nlm.nih.gov/pubmed/22405131
http://dx.doi.org/10.1186/bcr3137