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Amplification and high-level expression of heat shock protein 90 marks aggressive phenotypes of human epidermal growth factor receptor 2 negative breast cancer

INTRODUCTION: Although human epidermal growth factor receptor 2 (HER2) positive or estrogen receptor (ER) positive breast cancers are treated with clinically validated anti-HER2 or anti-estrogen therapies, intrinsic and acquired resistance to these therapies appears in a substantial proportion of br...

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Detalhes bibliográficos
Autores principales: Cheng, Qing, Chang, Jeffrey T, Geradts, Joseph, Neckers, Leonard M, Haystead, Timothy, Spector, Neil L, Lyerly, H Kim
Formato: Online Artigo Texto
Idioma:English
Publicado em: BioMed Central 2012
Assuntos:
Acesso em linha:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3446397/
https://www.ncbi.nlm.nih.gov/pubmed/22510516
http://dx.doi.org/10.1186/bcr3168