Cargando…

Amplification and high-level expression of heat shock protein 90 marks aggressive phenotypes of human epidermal growth factor receptor 2 negative breast cancer

INTRODUCTION: Although human epidermal growth factor receptor 2 (HER2) positive or estrogen receptor (ER) positive breast cancers are treated with clinically validated anti-HER2 or anti-estrogen therapies, intrinsic and acquired resistance to these therapies appears in a substantial proportion of br...

Descripción completa

Detalles Bibliográficos
Autores principales:	Cheng, Qing, Chang, Jeffrey T, Geradts, Joseph, Neckers, Leonard M, Haystead, Timothy, Spector, Neil L, Lyerly, H Kim
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2012
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3446397/ https://www.ncbi.nlm.nih.gov/pubmed/22510516 http://dx.doi.org/10.1186/bcr3168

Ejemplares similares

Heat shock protein 90-targeted photodynamic therapy enables treatment of subcutaneous and visceral tumors
por: Kaneko, Kensuke, et al.
Publicado: (2020)

Targeting Heat Shock Protein 90 for the Treatment of Malignant Pheochromocytoma
por: Giubellino, Alessio, et al.
Publicado: (2013)

HSP90-Specific nIR Probe Identifies Aggressive Prostate Cancers: Translation from Preclinical Models to a Human Phase I Study
por: Osada, Takuya, et al.
Publicado: (2022)

Leveraging ectopic Hsp90 expression to assay the presence of tumor cells and aggressive tumor phenotypes in breast specimens
por: Crouch, Brian, et al.
Publicado: (2017)

Combination of a novel heat shock protein 90-targeted photodynamic therapy with PD-1/PD-L1 blockade induces potent systemic antitumor efficacy and abscopal effect against breast cancers
por: Kaneko, Kensuke, et al.
Publicado: (2022)

Heat shock protein 90 promotes RNA helicase DDX5 accumulation and exacerbates hepatocellular carcinoma by inhibiting autophagy
por: Zhang, Ting, et al.
Publicado: (2021)

Post-translational modification and conformational state of Heat Shock Protein 90 differentially affect binding of chemically diverse small molecule inhibitors
por: Beebe, Kristin, et al.
Publicado: (2013)

Heat Shock Protein 90 (Hsp90) Expression and Breast Cancer
por: Zagouri, Flora, et al.
Publicado: (2012)

Antibodies to Heat Shock Proteins 90α and 90β in Psoriasis
por: Damasiewicz-Bodzek, Aleksandra, et al.
Publicado: (2020)

Proteomic analysis of proteome and histone post-translational modifications in heat shock protein 90 inhibition-mediated bladder cancer therapeutics
por: Li, Qingdi Quentin, et al.
Publicado: (2017)

Heat shock protein 90 in neurodegenerative diseases
por: Luo, Wenjie, et al.
Publicado: (2010)

Heat Shock Protein 90 in Alzheimer's Disease
por: Ou, Jiang-Rong, et al.
Publicado: (2014)

Heat shock protein 90 inhibition in the endothelium
por: Barabutis, Nektarios
Publicado: (2023)

High Expression of Heat Shock Protein 90 Is Associated with Tumor Aggressiveness and Poor Prognosis in Patients with Advanced Gastric Cancer
por: Wang, Jiahong, et al.
Publicado: (2013)

Potential role of heat shock protein 90 (Hsp90) in HIV uncoating
por: Joshi, Pheroze, et al.
Publicado: (2011)

Heat Shock Protein 90 (HSP90) and Her2 in Adenocarcinomas of the Esophagus
por: Slotta-Huspenina, Julia, et al.
Publicado: (2014)

Out with the old: Hsp90 finds amino acid residue more useful than co-chaperone protein
por: Zuehlke, Abbey D., et al.
Publicado: (2017)

Heat shock protein90 in lobular neoplasia of the breast
por: Zagouri, Flora, et al.
Publicado: (2008)

The Hexameric Structures of Human Heat Shock Protein 90
por: Lee, Cheng-Chung, et al.
Publicado: (2011)

Heat Shock Protein 90 regulates encystation in Entamoeba
por: Singh, Meetali, et al.
Publicado: (2015)

Effects of Heat Shock Protein 90 Inhibition In the Lungs
por: Uddin, Mohammad A., et al.
Publicado: (2020)

Sensitivity of epidermal growth factor receptor and ErbB2 exon 20 insertion mutants to Hsp90 inhibition
por: Xu, W, et al.
Publicado: (2007)

Molecular cloning, phylogenetic analysis and heat shock response of Babesia gibsoni heat shock protein 90
por: YAMASAKI, Masahiro, et al.
Publicado: (2016)

Simvastatin functions as a heat shock protein 90 inhibitor against triple‐negative breast cancer
por: Kou, Xinhui, et al.
Publicado: (2018)

Heat shock proteins in the physiology and pathophysiology of epidermal keratinocytes
por: Scieglinska, Dorota, et al.
Publicado: (2019)

Circulating heat shock protein 90 (Hsp90) and autoantibodies to Hsp90 are increased in patients with atopic dermatitis
por: Sitko, Krzysztof, et al.
Publicado: (2021)

Activity of the Heat Shock Protein 90 Inhibitor Ganetespib in Melanoma
por: Wu, Xinqi, et al.
Publicado: (2013)

Inhibition of Heat Shock Protein 90 Prevents HIV Rebound
por: Joshi, Pheroze, et al.
Publicado: (2016)

A secreted Heat shock protein 90 of Trichomonas vaginalis
por: Singh, Meetali, et al.
Publicado: (2018)

Heat Shock Protein 70 and 90 Family in Prostate Cancer
por: Fu, Xun, et al.
Publicado: (2022)

Heat shock protein 90 is required for sexual and asexual development, virulence, and heat shock response in Fusarium graminearum
por: Bui, Duc-Cuong, et al.
Publicado: (2016)

Identification and Characterization of Three Heat Shock Protein 90 (Hsp90) Homologs in the Brown Planthopper
por: Chen, Xuan, et al.
Publicado: (2020)

Identification of Isoform-Selective Ligands for the Middle Domain of Heat Shock Protein 90 (Hsp90)
por: Mak, Oi Wei, et al.
Publicado: (2019)

Extracellular Heat Shock Protein-90 (eHsp90): Everything You Need to Know
por: Jay, Daniel, et al.
Publicado: (2022)

Silencing of heat shock protein 90 (hsp90): Effect on development and infectivity of Ichthyophthirius multifiliis
por: Saleh, Mona, et al.
Publicado: (2023)

Molecular docking and pharmacophore studies of heterocyclic compounds as Heat shock protein 90 (Hsp90) Inhibitors
por: Baby, Suby T, et al.
Publicado: (2016)

Traditional and Novel Mechanisms of Heat Shock Protein 90 (HSP90) Inhibition in Cancer Chemotherapy Including HSP90 Cleavage
por: Park, Sangkyu, et al.
Publicado: (2019)

Spotlight on the microbes that produce heat shock protein 90-targeting antibiotics
por: Piper, Peter W., et al.
Publicado: (2012)

Heat shock protein 90 inhibitors repurposed against Entamoeba histolytica
por: Shahinas, Dea, et al.
Publicado: (2015)

Heat Shock Protein 90 Involvement in the Development of Idiopathic Epiretinal Membranes
por: Tosi, Gian Marco, et al.
Publicado: (2020)

Cannot write session to /tmp/vufind_sessions/sess_g6dumj3r3qb8pq1qc7rl6gr0ce