Hypogalactosylation of serum N-glycans fails to predict clinical response to methotrexate and TNF inhibition in rheumatoid arthritis

INTRODUCTION: Rheumatoid arthritis (RA) is associated with hypogalactosylation of immunoglobulin G (IgG). We examined whether a proxy measure for galactosylation of IgG N-glycans could predict response to therapy or was differentially affected by methotrexate (MTX) or TNF blockade. METHODS: Using a...

Descripción completa

Detalles Bibliográficos
Autores principales: Ercan, Altan, Cui, Jing, Hazen, Melissa M, Batliwalla, Franak, Royle, Louise, Rudd, Pauline M, Coblyn, Jonathan S, Shadick, Nancy, Weinblatt, Michael E, Gregersen, Peter, Lee, David M, Nigrovic, Peter A
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3446410/
https://www.ncbi.nlm.nih.gov/pubmed/22390545
http://dx.doi.org/10.1186/ar3756

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3446410/
https://www.ncbi.nlm.nih.gov/pubmed/22390545
http://dx.doi.org/10.1186/ar3756

Ejemplares similares