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Differential regulation of osteoclastogenesis by Notch2/Delta-like 1 and Notch1/Jagged1 axes

INTRODUCTION: Osteoclastogenesis plays an important role in the bone erosion of rheumatoid arthritis (RA). Recently, Notch receptors have been implicated in the development of osteoclasts. However, the responsible Notch ligands have not been identified yet. This study was undertaken to determine the...

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Detalles Bibliográficos
Autores principales: Sekine, Chiyoko, Koyanagi, Akemi, Koyama, Noriko, Hozumi, Katsuto, Chiba, Shigeru, Yagita, Hideo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3446412/
https://www.ncbi.nlm.nih.gov/pubmed/22390640
http://dx.doi.org/10.1186/ar3758