Rat tail static compression model mimics extracellular matrix metabolic imbalances of matrix metalloproteinases, aggrecanases, and tissue inhibitors of metalloproteinases in intervertebral disc degeneration

INTRODUCTION: The longitudinal degradation mechanism of extracellular matrix (ECM) in the interbertebral disc remains unclear. Our objective was to elucidate catabolic and anabolic gene expression profiles and their balances in intervertebral disc degeneration using a static compression model. METHO...

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Detalles Bibliográficos
Autores principales: Yurube, Takashi, Takada, Toru, Suzuki, Teppei, Kakutani, Kenichiro, Maeno, Koichiro, Doita, Minoru, Kurosaka, Masahiro, Nishida, Kotaro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3446417/
https://www.ncbi.nlm.nih.gov/pubmed/22394620
http://dx.doi.org/10.1186/ar3764

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3446417/
https://www.ncbi.nlm.nih.gov/pubmed/22394620
http://dx.doi.org/10.1186/ar3764

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