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What is the future of CCR5 antagonists in rheumatoid arthritis?

Fleishaker and colleagues reported on a double-blind placebo controlled clinical trial of a C-C chemokine-receptor type 5 (CCR5) antagonist, maraviroc, in rheumatoid arthritis (RA) patients with inadequate response to methotrexate, showing that it was ineffective. Two additional CCR5 antagonists, SC...

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Detalles Bibliográficos
Autores principales: Takeuchi, Tsutomu, Kameda, Hideto
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3446428/
https://www.ncbi.nlm.nih.gov/pubmed/22494450
http://dx.doi.org/10.1186/ar3775