Cargando…

Identification of low-frequency TRAF3IP2 coding variants in psoriatic arthritis patients and functional characterization

INTRODUCTION: In recent genome-wide association studies for psoriatic arthritis (PsA) and psoriasis vulgaris, common coding variants in the TRAF3IP2 gene were identified to contribute to susceptibility to both disease entities. The risk allele of p.Asp10Asn (rs33980500) proved to be most significant...

Descripción completa

Detalles Bibliográficos
Autores principales: Böhm, Beate, Burkhardt, Harald, Uebe, Steffen, Apel, Maria, Behrens, Frank, Reis, André, Hüffmeier, Ulrike
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3446458/
https://www.ncbi.nlm.nih.gov/pubmed/22513239
http://dx.doi.org/10.1186/ar3807