The Sp1 transcription factor is essential for the expression of gliostatin/thymidine phosphorylase in rheumatoid fibroblast-like synoviocytes

INTRODUCTION: Gliostatin/thymidine phosphorylase (GLS/TP) has angiogenic and arthritogenic activities, and aberrant GLS production has been observed in the active synovial membranes of rheumatoid arthritis (RA) patients. The human GLS gene promoter contains at least seven consensus binding sites for...

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Detalles Bibliográficos
Autores principales: Ikuta, Kenji, Waguri-Nagaya, Yuko, Kikuchi, Kae, Yamagami, Takaya, Nozaki, Masahiro, Aoyama, Mineyoshi, Asai, Kiyofumi, Otsuka, Takanobu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3446461/
https://www.ncbi.nlm.nih.gov/pubmed/22534375
http://dx.doi.org/10.1186/ar3811

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3446461/
https://www.ncbi.nlm.nih.gov/pubmed/22534375
http://dx.doi.org/10.1186/ar3811

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