Cargando…

PAD4 is not essential for disease in the K/BxN murine autoantibody-mediated model of arthritis

INTRODUCTION: Both murine and human genome-wide association studies have implicated peptidyl arginine deiminase (PAD4) as a susceptibility gene in rheumatoid arthritis (RA). In addition, patients with RA commonly have autoantibodies which recognize PAD4 or and/or citrullinated peptides. This study a...

Descripción completa

Detalles Bibliográficos
Autores principales: Rohrbach, Amanda S, Hemmers, Saskia, Arandjelovic, Sanja, Corr, Maripat, Mowen, Kerri A
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3446481/
https://www.ncbi.nlm.nih.gov/pubmed/22551352
http://dx.doi.org/10.1186/ar3829