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The effects of oxygen tension and antiaging factor Klotho on Wnt signaling in nucleus pulposus cells
INTRODUCTION: The goals of this study were to examine the oxemic regulation of Wnt signaling to explore whether Wnt signaling accelerates the age-related degeneration of nucleus pulposus cells, and if so, to define the mechanism underlying this effect. We investigated the expression of Klotho, a new...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3446482/ https://www.ncbi.nlm.nih.gov/pubmed/22551380 http://dx.doi.org/10.1186/ar3830 |