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Efficacy of an immunotoxin to folate receptor beta in the intra-articular treatment of antigen-induced arthritis

INTRODUCTION: We previously demonstrated that synovial sublining macrophages express folate receptor beta (FRβ). The aim of this study was to evaluate the efficacy of intra-articular administration of a recombinant immunotoxin to FRβ for treating rat antigen-induced arthritis. METHODS: A monoclonal...

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Detalles Bibliográficos
Autores principales: Nagai, Taku, Kyo, Akira, Hasui, Kazuhisa, Takao, Sonshin, Matsuyama, Takami
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3446483/
https://www.ncbi.nlm.nih.gov/pubmed/22551402
http://dx.doi.org/10.1186/ar3831