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Limited effect of anti-rheumatic treatment on 15-prostaglandin dehydrogenase in rheumatoid arthritis synovial tissue

INTRODUCTION: Rheumatoid arthritis (RA) is a chronic inflammatory disease in which prostaglandin E(2 )(PGE(2)) displays an important pathogenic role. The enzymes involved in its synthesis are highly expressed in the inflamed synovium, while little is known about 15- prostaglandin dehydrogenase (15-P...

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Detalles Bibliográficos
Autores principales: Gheorghe, Karina Roxana, Sadique, Syed, Leclerc, Patrick, Idborg, Helena, Wobst, Ivonne, Catrina, Anca Irinel, Jakobsson, Per-Johan, Korotkova, Marina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3446502/
https://www.ncbi.nlm.nih.gov/pubmed/22616846
http://dx.doi.org/10.1186/ar3851