Cargando…

Limited effect of anti-rheumatic treatment on 15-prostaglandin dehydrogenase in rheumatoid arthritis synovial tissue

INTRODUCTION: Rheumatoid arthritis (RA) is a chronic inflammatory disease in which prostaglandin E(2 )(PGE(2)) displays an important pathogenic role. The enzymes involved in its synthesis are highly expressed in the inflamed synovium, while little is known about 15- prostaglandin dehydrogenase (15-P...

Descripción completa

Detalles Bibliográficos
Autores principales:	Gheorghe, Karina Roxana, Sadique, Syed, Leclerc, Patrick, Idborg, Helena, Wobst, Ivonne, Catrina, Anca Irinel, Jakobsson, Per-Johan, Korotkova, Marina
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2012
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3446502/ https://www.ncbi.nlm.nih.gov/pubmed/22616846 http://dx.doi.org/10.1186/ar3851

Ejemplares similares

Effects of anti-rheumatic treatments on the prostaglandin E(2 )biosynthetic pathway in synovial tissue and synovial fluid cells from patients with rheumatoid arthritis
por: Korotkova, M, et al.
Publicado: (2005)

Expression of 5-lipoxygenase and 15-lipoxygenase in rheumatoid arthritis synovium and effects of intraarticular glucocorticoids
por: Gheorghe, Karina Roxana, et al.
Publicado: (2009)

Microsomal Prostaglandin E Synthase-1 in Rheumatic Diseases
por: Korotkova, Marina, et al.
Publicado: (2011)

IL-1β/HMGB1 Complexes Promote The PGE(2) Biosynthesis Pathway in Synovial Fibroblasts
por: Leclerc, P, et al.
Publicado: (2013)

Synovial membrane immunohistology in early-untreated rheumatoid arthritis reveals high expression of catabolic bone markers that is modulated by methotrexate
por: Revu, Shankar, et al.
Publicado: (2013)

Prostaglandin E(2) Synthesizing Enzymes in Rheumatoid Arthritis B Cells and the Effects of B Cell Depleting Therapy on Enzyme Expression
por: Gheorghe, Karina Roxana, et al.
Publicado: (2011)

Effects of anti-rheumatic treatments on expression of microsomal prostaglandin E synthase-1 in rheumatoid arthritis synovium
por: Korotkova, M, et al.
Publicado: (2004)

Monocytes are essential for inhibition of synovial T-cell glucocorticoid-mediated apoptosis in rheumatoid arthritis
por: Makrygiannakis, Dimitrios, et al.
Publicado: (2008)

Effect of infliximab on mRNA expression profiles in synovial tissue of rheumatoid arthritis patients
por: Lindberg, Johan, et al.
Publicado: (2006)

Synovial expression of IL-15 in rheumatoid arthritis is not influenced by blockade of tumour necrosis factor
por: Ernestam, Sofia, et al.
Publicado: (2006)

Impact of Temporomandibular Joint Pain in Rheumatoid Arthritis
por: Ahmed, Neveen, et al.
Publicado: (2013)

Local administration of glucocorticoids decreases synovial citrullination in rheumatoid arthritis
por: Makrygiannakis, Dimitrios, et al.
Publicado: (2012)

Expression of Prostaglandin E(2) Enzymes in the Synovium of Arthralgia Patients at Risk of Developing Rheumatoid Arthritis and in Early Arthritis Patients
por: de Hair, Maria J. H., et al.
Publicado: (2015)

Arg126 and Asp49 Are Essential for the Catalytic Function of Microsomal Prostaglandin E(2) Synthase 1 and Ser127 Is Not
por: Raouf, Joan, et al.
Publicado: (2016)

Extracellular miR-574-5p Induces Osteoclast Differentiation via TLR 7/8 in Rheumatoid Arthritis
por: Hegewald, Anett B., et al.
Publicado: (2020)

Prostaglandin E(2 )is an enhancer for IL-1β-induced expression of membrane-associated prostaglandin E synthase in rheumatoid synovial fibroblasts
por: Kojima, F, et al.
Publicado: (2003)

Prostaglandin production by rheumatoid synovial cells: stimulation by a factor from human mononuclear Cells
Publicado: (1977)

Expression of microsomal prostaglandin E synthase-1 in muscle tissue of patients with idiopathic inflammatory myopathies
por: Korotkova, M, et al.
Publicado: (2005)

Biosynthesis of prostaglandin 15dPGJ(2) -glutathione and 15dPGJ(2)-cysteine conjugates in macrophages and mast cells via MGST3
por: Steinmetz-Späh, Julia, et al.
Publicado: (2022)

Targeted lipidomics analysis identified altered serum lipid profiles in patients with polymyositis and dermatomyositis
por: Raouf, Joan, et al.
Publicado: (2018)

Prostaglandins and Rheumatoid Arthritis
por: Fattahi, Mohammad Javad, et al.
Publicado: (2012)

Inhibition of Microsomal Prostaglandin E Synthase-1 in Cancer-Associated Fibroblasts Suppresses Neuroblastoma Tumor Growth
por: Kock, Anna, et al.
Publicado: (2018)

Microsomal prostaglandin E synthase-1 gene deletion impairs neuro-immune circuitry of the cholinergic anti-inflammatory pathway in endotoxaemic mouse spleen
por: Revathikumar, Priya, et al.
Publicado: (2018)

Correction: Microsomal prostaglandin E synthase-1 gene deletion impairs neuro-immune circuitry of the cholinergic anti-inflammatory pathway in endotoxaemic mouse spleen
por: Revathikumar, Priya, et al.
Publicado: (2018)

Anticitrullinated protein antibodies facilitate migration of synovial tissue-derived fibroblasts
por: Sun, Meng, et al.
Publicado: (2019)

Low levels of apoptosis and high FLIP expression in early rheumatoid arthritis synovium
por: Ulfgren, A-K, et al.
Publicado: (2002)

Structural Insights into Novel 15-Prostaglandin Dehydrogenase Inhibitors
por: Mallipeddi, Prema L., et al.
Publicado: (2021)

R-Flurbiprofen Traps Prostaglandins within Cells by Inhibition of Multidrug Resistance-Associated Protein-4
por: Wobst, Ivonne, et al.
Publicado: (2016)

MicroRNA-218 promotes prostaglandin E2 to inhibit osteogenic differentiation in synovial mesenchymal stem cells by targeting 15-hydroxyprostaglandin dehydrogenase [NAD(+)]
por: Cong, Ruijun, et al.
Publicado: (2017)

Seropositivity combined with smoking is associated with increased prevalence of periodontitis in patients with rheumatoid arthritis
por: Eriksson, Kaja, et al.
Publicado: (2018)

IMMUNOREACTANTS IN RHEUMATOID SYNOVIAL EFFUSIONS
por: Zvaifler, Nathan J.
Publicado: (1971)

Serum metabolomic profiling predicts synovial gene expression in rheumatoid arthritis
por: Narasimhan, Rekha, et al.
Publicado: (2018)

Gout, Rheumatism, and Rheumatoid Arthritis
Publicado: (1900)

Chronic Rheumatism and Rheumatoid Arthritis
por: Lindsay, J.
Publicado: (1908)

Targeting of anti-citrullinated protein/peptide antibodies in rheumatoid arthritis using peptides mimicking endogenously citrullinated fibrinogen antigens
por: Fernandes-Cerqueira, Cátia, et al.
Publicado: (2015)

Current view on the pathogenic role of anti-citrullinated protein antibodies in rheumatoid arthritis
por: Catrina, Anca, et al.
Publicado: (2021)

Effects of immunosuppressive treatment on microsomal prostaglandin E synthase 1 and cyclooxygenases expression in muscle tissue of patients with polymyositis or dermatomyositis
por: Korotkova, M, et al.
Publicado: (2008)

mPGES-1 and prostaglandin E(2): vital role in inflammation, hypoxic response, and survival
por: Siljehav, Veronica, et al.
Publicado: (2012)

The Rheumatoid Factor in Serum and Synovial Fluid
por: Krehl, Willard A., et al.
Publicado: (1957)

Synovial Histopathology in Early Rheumatoid Arthritis
por: Hirohata, Shunsei, et al.
Publicado: (2000)

Cannot write session to /tmp/vufind_sessions/sess_mra29vrad892s62s94qbs5eb80