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A new immunoprecipitation-real time quantitative PCR assay for anti-Th/To and anti-U3RNP antibody detection in systemic sclerosis

INTRODUCTION: Classic anti-nucleolar antibodies anti-Th/To and U3 ribonucleoprotein (-U3RNP) can help in the diagnosis, prediction of organ involvement and prognosis in systemic sclerosis (SSc); however, no validated commercial assay is available. We aimed at establishing a novel quantitative real t...

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Detalles Bibliográficos
Autores principales: Ceribelli, Angela, Satoh, Minoru, Chan, Edward KL
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3446509/
https://www.ncbi.nlm.nih.gov/pubmed/22643159
http://dx.doi.org/10.1186/ar3858