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Establishment and characterization of a sustained delayed-type hypersensitivity model with arthritic manifestations in C57BL/6J mice

INTRODUCTION: Rheumatoid arthritis (RA) is a chronic progressive, inflammatory and destructive autoimmune disease, characterised by synovial joint inflammation and bone erosion. To better understand the pathophysiology and underlying immune mechanisms of RA various models of arthritis have been deve...

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Detalles Bibliográficos
Autores principales: Atkinson, Sara M, Usher, Pernille A, Kvist, Peter H, Markholst, Helle, Haase, Claus, Nansen, Anneline
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3446517/
https://www.ncbi.nlm.nih.gov/pubmed/22676339
http://dx.doi.org/10.1186/ar3867