Interleukin-7-aggravated joint inflammation and tissue destruction in collagen-induced arthritis is associated with T-cell and B-cell activation

INTRODUCTION: We sought to investigate the capacity of interleukin (IL)-7 to enhance collagen-induced arthritis and to study by what mechanisms this is achieved. METHODS: Mice received multiple injections with IL-7 or phosphate-buffered saline (PBS) as a control. Arthritis severity and incidence wer...

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Detalles Bibliográficos
Autores principales: Hartgring, Sarita AY, Willis, Cynthia R, Bijlsma, Johannes WJ, Lafeber, Floris PJG, van Roon, Joel AG
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3446520/
https://www.ncbi.nlm.nih.gov/pubmed/22676399
http://dx.doi.org/10.1186/ar3870

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3446520/
https://www.ncbi.nlm.nih.gov/pubmed/22676399
http://dx.doi.org/10.1186/ar3870

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