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C5a and its receptors in human anti-neutrophil cytoplasmic antibody (ANCA)-associated vasculitis

INTRODUCTION: The complement system is crucial for the development of antineutrophil cytoplasmic antibody (ANCA)-associated vasculitis (AAV). In particular, C5a plays a central role. In this study, plasma and urinary levels of C5a as well as renal C5a receptors (CD88 and C5L2) expression were invest...

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Detalles Bibliográficos
Autores principales: Yuan, Jun, Gou, Shen-Ju, Huang, Jing, Hao, Jian, Chen, Min, Zhao, Ming-Hui
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3446523/
https://www.ncbi.nlm.nih.gov/pubmed/22691190
http://dx.doi.org/10.1186/ar3873