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Investigation of the role of endosomal Toll-like receptors in murine collagen-induced arthritis reveals a potential role for TLR7 in disease maintenance

INTRODUCTION: Endosomal toll-like receptors (TLRs) have recently emerged as potential contributors to the inflammation observed in human and rodent models of rheumatoid arthritis (RA). This study aims to evaluate the role of endosomal TLRs and in particular TLR7 in the murine collagen induced arthri...

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Detalles Bibliográficos
Autores principales: Alzabin, Saba, Kong, Philip, Medghalchi, Mino, Palfreeman, Andrew, Williams, Richard, Sacre, Sandra
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3446525/
https://www.ncbi.nlm.nih.gov/pubmed/22691272
http://dx.doi.org/10.1186/ar3875