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CD109, a TGF-β co-receptor, attenuates extracellular matrix production in scleroderma skin fibroblasts
INTRODUCTION: Scleroderma or systemic sclerosis (SSc) is a complex connective tissue disease characterized by fibrosis of skin and internal organs. Transforming growth factor beta (TGF-β) plays a key role in the pathogenesis of SSc fibrosis. We have previously identified CD109 as a novel TGF-β co-re...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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BioMed Central
2012
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3446527/ https://www.ncbi.nlm.nih.gov/pubmed/22694813 http://dx.doi.org/10.1186/ar3877 |