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CD109, a TGF-β co-receptor, attenuates extracellular matrix production in scleroderma skin fibroblasts

INTRODUCTION: Scleroderma or systemic sclerosis (SSc) is a complex connective tissue disease characterized by fibrosis of skin and internal organs. Transforming growth factor beta (TGF-β) plays a key role in the pathogenesis of SSc fibrosis. We have previously identified CD109 as a novel TGF-β co-re...

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Detalles Bibliográficos
Autores principales:	Man, Xiao-Yong, Finnson, Kenneth W, Baron, Murray, Philip, Anie
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2012
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3446527/ https://www.ncbi.nlm.nih.gov/pubmed/22694813 http://dx.doi.org/10.1186/ar3877

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