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Immune Sculpting of Norepinephrine on MHC-I, B7-1, IDO and B7-H1 Expression and Regulation of Proliferation and Invasion in Pancreatic Carcinoma Cells

BACKGROUND: The sympathetic neurotransmitter Norepinephrine (NE) contributes to tumorigenesis and cancer progression. This study aims to investigate the role of NE in modulating the immune phenotype and allowing pancreatic carcinoma (PC) cells to escape the immune response. METHODS: Varied concentra...

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Detalles Bibliográficos
Autores principales: Wang, Liancai, Liu, Han, Chen, Xiangli, Zhang, Min, Xie, Keping, Ma, Qingyong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3446877/
https://www.ncbi.nlm.nih.gov/pubmed/23029049
http://dx.doi.org/10.1371/journal.pone.0045491