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Immune Sculpting of Norepinephrine on MHC-I, B7-1, IDO and B7-H1 Expression and Regulation of Proliferation and Invasion in Pancreatic Carcinoma Cells
BACKGROUND: The sympathetic neurotransmitter Norepinephrine (NE) contributes to tumorigenesis and cancer progression. This study aims to investigate the role of NE in modulating the immune phenotype and allowing pancreatic carcinoma (PC) cells to escape the immune response. METHODS: Varied concentra...
Autores principales: | Wang, Liancai, Liu, Han, Chen, Xiangli, Zhang, Min, Xie, Keping, Ma, Qingyong |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3446877/ https://www.ncbi.nlm.nih.gov/pubmed/23029049 http://dx.doi.org/10.1371/journal.pone.0045491 |
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