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Interferon Regulatory Factor-8 Is Important for Histone Deacetylase Inhibitor-Mediated Antitumor Activity

The notion that epigenetic alterations in neoplasia are reversible has provided the rationale to identify epigenetic modifiers for their ability to induce or enhance tumor cell death. Histone deacetylase inhibitors (HDACi) represent one such class of anti-neoplastic agents. Despite great interest fo...

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Detalles Bibliográficos
Autores principales: Banik, Debarati, Khan, A. Nazmul H., Walseng, Even, Segal, Brahm H., Abrams, Scott I.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3446900/
https://www.ncbi.nlm.nih.gov/pubmed/23028998
http://dx.doi.org/10.1371/journal.pone.0045422