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Hypoxia Enhances the Proliferative Response of Macrophages to CSF-1 and Their Pro-Survival Response to TNF

In chronic inflammatory lesions there are increased numbers of macrophages with a possible contribution of enhanced survival/proliferation due, for example, to cytokine action; such lesions are often hypoxic. Prior studies have found that culture in low oxygen can promote monocyte/macrophage surviva...

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Detalles Bibliográficos
Autores principales: Hamilton, John A., Lacey, Derek C., Turner, Amanda, de Kok, Bernard, Huynh, Jennifer, Scholz, Glen M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3446916/
https://www.ncbi.nlm.nih.gov/pubmed/23029275
http://dx.doi.org/10.1371/journal.pone.0045853