A Novel Small Molecule FL118 That Selectively Inhibits Survivin, Mcl-1, XIAP and cIAP2 in a p53-Independent Manner, Shows Superior Antitumor Activity

Drug/radiation resistance to treatment and tumor relapse are major obstacles in identifying a cure for cancer. Development of novel agents that address these challenges would therefore be of the upmost importance in the fight against cancer. In this regard, studies show that the antiapoptotic protei...

Descripción completa

Detalles Bibliográficos
Autores principales: Ling, Xiang, Cao, Shousong, Cheng, Qiuying, Keefe, James T., Rustum, Youcef M., Li, Fengzhi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3446924/
https://www.ncbi.nlm.nih.gov/pubmed/23029106
http://dx.doi.org/10.1371/journal.pone.0045571

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3446924/
https://www.ncbi.nlm.nih.gov/pubmed/23029106
http://dx.doi.org/10.1371/journal.pone.0045571

Ejemplares similares