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U2AF1 Mutations in Chinese Patients with Acute Myeloid Leukemia and Myelodysplastic Syndrome

Somatic mutations of U2AF1 gene have recently been identified in myelodysplastic syndrome (MDS) and acute myeloid leukemia (AML). In this study, we analyzed the frequency and clinical impact of U2AF1 mutations in a cohort of 452 Chinese patients with myeloid neoplasms. Mutations in U2AF1 were found...

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Detalles Bibliográficos
Autores principales: Qian, Jun, Yao, Dong-ming, Lin, Jiang, Qian, Wei, Wang, Cui-zhu, Chai, Hai-yan, Yang, Jing, Li, Yun, Deng, Zhao-qun, Ma, Ji-chun, Chen, Xing-xing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3446943/
https://www.ncbi.nlm.nih.gov/pubmed/23029227
http://dx.doi.org/10.1371/journal.pone.0045760