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Foxp3(+) Regulatory T Cells among Tuberculosis Patients: Impact on Prognosis and Restoration of Antigen Specific IFN-γ Producing T Cells

CD4(+)CD25(+)Foxp3(+) Regulatory T cells (Treg) and programmed death-1 (PD-1) molecules have emerged as pivotal players in immune suppression of chronic diseases. However, their impact on the disease severity, therapeutic response and restoration of immune response in human tuberculosis remains uncl...

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Detalles Bibliográficos
Autores principales: Singh, Amar, Dey, Aparajita Ballave, Mohan, Anant, Sharma, Prabhat Kumar, Mitra, Dipendra Kumar
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3446959/
https://www.ncbi.nlm.nih.gov/pubmed/23028594
http://dx.doi.org/10.1371/journal.pone.0044728