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Salinomycin Induces Autophagy in Colon and Breast Cancer Cells with Concomitant Generation of Reactive Oxygen Species

BACKGROUND: Salinomycin is a polyether ionophore antibiotic that has recently been shown to induce cell death in human cancer cells displaying multiple mechanisms of drug resistance. The underlying mechanisms leading to cell death after salinomycin treatment have not been well characterized. We ther...

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Detalles Bibliográficos
Autores principales: Verdoodt, Berlinda, Vogt, Markus, Schmitz, Inge, Liffers, Sven-Thorsten, Tannapfel, Andrea, Mirmohammadsadegh, Alireza
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3446972/
https://www.ncbi.nlm.nih.gov/pubmed/23028492
http://dx.doi.org/10.1371/journal.pone.0044132