The Therapeutic Profile of Rolipram, PDE Target and Mechanism of Action as a Neuroprotectant following Spinal Cord Injury

The extent of damage following spinal cord injury (SCI) can be reduced by various neuroprotective regimens that include maintaining levels of cyclic adenosine monophosphate (cyclic AMP), via administration of the phosphodiesterase 4 (PDE4) inhibitor Rolipram. The current study sought to determine th...

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Detalles Bibliográficos
Autores principales: Schaal, Sandra Marie, Garg, Maneesh Sen, Ghosh, Mousumi, Lovera, Lilie, Lopez, Michael, Patel, Monal, Louro, Jack, Patel, Samik, Tuesta, Luis, Chan, Wai-Man, Pearse, Damien Daniel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3446989/
https://www.ncbi.nlm.nih.gov/pubmed/23028463
http://dx.doi.org/10.1371/journal.pone.0043634

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3446989/
https://www.ncbi.nlm.nih.gov/pubmed/23028463
http://dx.doi.org/10.1371/journal.pone.0043634

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