Less than 5 Netrin-1 molecules initiate attraction but 200 Sema3A molecules are necessary for repulsion

Guidance molecules, such as Sema3A or Netrin-1, induce growth cone (GC) repulsion or attraction. In order to determine the speed of action and efficiency of these guidance cues we developed an experimental procedure to deliver controlled amounts of these molecules. Lipid vesicles encapsulating 10–10...

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Detalles Bibliográficos
Autores principales: Pinato, Giulietta, Cojoc, Dan, Lien, Linh Thuy, Ansuini, Alessio, Ban, Jelena, D’Este, Elisa, Torre, Vincent
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2012
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3447186/
https://www.ncbi.nlm.nih.gov/pubmed/22997549
http://dx.doi.org/10.1038/srep00675

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3447186/
https://www.ncbi.nlm.nih.gov/pubmed/22997549
http://dx.doi.org/10.1038/srep00675

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