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Less than 5 Netrin-1 molecules initiate attraction but 200 Sema3A molecules are necessary for repulsion
Guidance molecules, such as Sema3A or Netrin-1, induce growth cone (GC) repulsion or attraction. In order to determine the speed of action and efficiency of these guidance cues we developed an experimental procedure to deliver controlled amounts of these molecules. Lipid vesicles encapsulating 10–10...
| Autores principales: | , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group
2012
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3447186/ https://www.ncbi.nlm.nih.gov/pubmed/22997549 http://dx.doi.org/10.1038/srep00675 |