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A Novel Vaccine Using Nanoparticle Platform to Present Immunogenic M2e against Avian Influenza Infection

Using peptide nanoparticle technology, we have designed two novel vaccine constructs representing M2e in monomeric (Mono-M2e) and tetrameric (Tetra-M2e) forms. Groups of specific pathogen free (SPF) chickens were immunized intramuscularly with Mono-M2e or Tetra-M2e with and without an adjuvant. Two...

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Detalles Bibliográficos
Autores principales: Babapoor, Sankhiros, Neef, Tobias, Mittelholzer, Christian, Girshick, Theodore, Garmendia, Antonio, Shang, Hongwei, Khan, Mazhar I., Burkhard, Peter
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3447297/
https://www.ncbi.nlm.nih.gov/pubmed/23074652
http://dx.doi.org/10.1155/2011/126794