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A Novel Vaccine Using Nanoparticle Platform to Present Immunogenic M2e against Avian Influenza Infection
Using peptide nanoparticle technology, we have designed two novel vaccine constructs representing M2e in monomeric (Mono-M2e) and tetrameric (Tetra-M2e) forms. Groups of specific pathogen free (SPF) chickens were immunized intramuscularly with Mono-M2e or Tetra-M2e with and without an adjuvant. Two...
Autores principales: | Babapoor, Sankhiros, Neef, Tobias, Mittelholzer, Christian, Girshick, Theodore, Garmendia, Antonio, Shang, Hongwei, Khan, Mazhar I., Burkhard, Peter |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Hindawi Publishing Corporation
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3447297/ https://www.ncbi.nlm.nih.gov/pubmed/23074652 http://dx.doi.org/10.1155/2011/126794 |
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