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PPARα-Independent Arterial Smooth Muscle Relaxant Effects of PPARα Agonists

We sought to determine direct vascular effects of peroxisome proliferator-activated receptor alpha (PPARα) agonists using isolated mouse aortas and middle cerebral arteries (MCAs). The PPARα agonists GW7647, WY14643, and gemfibrozil acutely relaxed aortas held under isometric tension and dilated pre...

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Detalles Bibliográficos
Autores principales: Silswal, Neerupma, Parelkar, Nikhil K., Wacker, Michael J., Badr, Mostafa, Andresen, Jon
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3447381/
https://www.ncbi.nlm.nih.gov/pubmed/23008696
http://dx.doi.org/10.1155/2012/302495