DNA Damage and Repair in Human Cancer: Molecular Mechanisms and Contribution to Therapy-Related Leukemias

Most antitumour therapies damage tumour cell DNA either directly or indirectly. Without repair, damage can result in genetic instability and eventually cancer. The strong association between the lack of DNA damage repair, mutations and cancer is dramatically demonstrated by a number of cancer-prone...

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Detalles Bibliográficos
Autores principales: Casorelli, Ida, Bossa, Cecilia, Bignami, Margherita
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2012
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3447578/
https://www.ncbi.nlm.nih.gov/pubmed/23066388
http://dx.doi.org/10.3390/ijerph9082636

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3447578/
https://www.ncbi.nlm.nih.gov/pubmed/23066388
http://dx.doi.org/10.3390/ijerph9082636

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