Design, Synthesis, and Antitumor Evaluation of Novel Pyrazolo[3,4-d]pyrimidine Derivatives

A new series of pyrazolo[3,4-d]pyrimidines has been synthesized. The new compounds were tested for their antitumor activity on 60 different cell lines, and some of the compounds were found to have potent antitumor activity. In particular, 2-hydroxybenzaldehyde [1-(4-chlorophenyl)-3-methyl-1H-pyrazol...

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Detalles Bibliográficos
Autores principales: Kandeel, Manal M., Mohamed, Lamia W., Abd El Hamid, Mohammed K., Negmeldin, Ahmed T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Österreichische Apotheker-Verlagsgesellschaft 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3447607/
https://www.ncbi.nlm.nih.gov/pubmed/23008804
http://dx.doi.org/10.3797/scipharm.1204-23

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3447607/
https://www.ncbi.nlm.nih.gov/pubmed/23008804
http://dx.doi.org/10.3797/scipharm.1204-23

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