Improvement of the Prediction Power of the CoMFA and CoMSIA Models on Histamine H3 Antagonists by Different Variable Selection Methods

The aim of this study is to enhance the predictivity power of CoMFA and CoMSIA models by means of different variable selection algorithms. The genetic algorithm (GA), successive projection algorithm (SPA), stepwise multiple linear regression (SW-MLR), and the enhanced replacement method (ERM) were u...

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Detalles Bibliográficos
Autores principales: Ghasemi, Jahan B., Tavakoli, Hossein
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Österreichische Apotheker-Verlagsgesellschaft 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3447613/
https://www.ncbi.nlm.nih.gov/pubmed/23008805
http://dx.doi.org/10.3797/scipharm.1204-19

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3447613/
https://www.ncbi.nlm.nih.gov/pubmed/23008805
http://dx.doi.org/10.3797/scipharm.1204-19

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