Stable expression of promyelocytic leukaemia (PML) protein in telomerase positive MCF7 cells results in alternative lengthening of telomeres phenotype

BACKGROUND: Cancer cells can employ telomerase or the alternative lengthening of telomeres (ALT) pathway for telomere maintenance. Cancer cells that use the ALT pathway exhibit distinct phenotypes such as heterogeneous telomeres and specialised Promyelocytic leukaemia (PML) nuclear foci called APBs....

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Detalles Bibliográficos
Autores principales: Yong, Jacklyn W Y, Yeo, Xiujun, Khan, Md Matiullah, Lee, Martin B, Prakash Hande, M
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2012
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3447653/
https://www.ncbi.nlm.nih.gov/pubmed/22925423
http://dx.doi.org/10.1186/2041-9414-3-5

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3447653/
https://www.ncbi.nlm.nih.gov/pubmed/22925423
http://dx.doi.org/10.1186/2041-9414-3-5

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