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Reduced osteoblast activity in the mice lacking TR4 nuclear receptor leads to osteoporosis
BACKGROUND: Early studies suggested that TR4 nuclear receptor might play important roles in the skeletal development, yet its detailed mechanism remains unclear. METHODS: We generated TR4 knockout mice and compared skeletal development with their wild type littermates. Primary bone marrow cells were...
Autores principales: | , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3447707/ https://www.ncbi.nlm.nih.gov/pubmed/22676849 http://dx.doi.org/10.1186/1477-7827-10-43 |