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Efficacy of sodium butyrate adjunct therapy in shigellosis: a randomized, double-blind, placebo-controlled clinical trial

BACKGROUND: Treatment of shigellosis in rabbits with butyrate reduces clinical severity and counteracts the downregulation of cathelicidin (CAP-18) in the large intestinal epithelia. Here, we aimed to evaluate whether butyrate can be used as an adjunct to antibiotics in the treatment of shigellosis...

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Detalles Bibliográficos
Autores principales: Raqib, Rubhana, Sarker, Protim, Mily, Akhirunnesa, Alam, Nur Haque, Arifuzzaman, Abu Saleh Mohammed, Rekha, Rokeya Sultana, Andersson, Jan, Gudmundsson, Gudmundur H, Cravioto, Alejandro, Agerberth, Birgitta
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3447723/
https://www.ncbi.nlm.nih.gov/pubmed/22574737
http://dx.doi.org/10.1186/1471-2334-12-111