A Cell-Based Screen Reveals that the Albendazole Metabolite, Albendazole Sulfone, Targets Wolbachia

Wolbachia endosymbionts carried by filarial nematodes give rise to the neglected diseases African river blindness and lymphatic filariasis afflicting millions worldwide. Here we identify new Wolbachia-disrupting compounds by conducting high-throughput cell-based chemical screens using a Wolbachia-in...

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Detalles Bibliográficos
Autores principales: Serbus, Laura R., Landmann, Frederic, Bray, Walter M., White, Pamela M., Ruybal, Jordan, Lokey, R. Scott, Debec, Alain, Sullivan, William
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3447747/
https://www.ncbi.nlm.nih.gov/pubmed/23028321
http://dx.doi.org/10.1371/journal.ppat.1002922

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3447747/
https://www.ncbi.nlm.nih.gov/pubmed/23028321
http://dx.doi.org/10.1371/journal.ppat.1002922

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