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Structural Organization of Pregenomic RNA and the Carboxy-Terminal Domain of the Capsid Protein of Hepatitis B Virus

The Hepatitis B Virus (HBV) double-stranded DNA genome is reverse transcribed from its RNA pregenome (pgRNA) within the virus core (or capsid). Phosphorylation of the arginine-rich carboxy-terminal domain (CTD) of the HBV capsid protein (Cp183) is essential for pgRNA encapsidation and reverse transc...

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Detalles Bibliográficos
Autores principales: Wang, Joseph C.-Y., Dhason, Mary S., Zlotnick, Adam
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3447754/
https://www.ncbi.nlm.nih.gov/pubmed/23028319
http://dx.doi.org/10.1371/journal.ppat.1002919