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A Role for microRNA-155 Modulation in the Anti-HIV-1 Effects of Toll-Like Receptor 3 Stimulation in Macrophages

HIV-1 infection of macrophages plays a key role in viral pathogenesis and progression to AIDS. Polyinosine-polycytidylic acid (poly(I∶C); a synthetic analog of dsRNA) and bacterial lipopolysaccharide (LPS), the ligands for Toll-like receptors (TLR) TLR3 and TLR4, respectively, are known to decrease...

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Detalles Bibliográficos
Autores principales: Swaminathan, Gokul, Rossi, Fiorella, Sierra, Luz-Jeannette, Gupta, Archana, Navas-Martín, Sonia, Martín-García, Julio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3447756/
https://www.ncbi.nlm.nih.gov/pubmed/23028330
http://dx.doi.org/10.1371/journal.ppat.1002937